{"id":16313,"date":"2020-03-21T10:03:41","date_gmt":"2020-03-21T14:03:41","guid":{"rendered":"https:\/\/phrg.ca\/le-groupe\/chercheurs\/"},"modified":"2025-10-09T15:36:55","modified_gmt":"2025-10-09T19:36:55","slug":"chercheurs","status":"publish","type":"page","link":"https:\/\/phrg.ca\/en\/le-groupe\/chercheurs\/","title":{"rendered":"Principal investigators"},"content":{"rendered":"<p>[vc_row css=&#8221;.vc_custom_1584807143299{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text]<span class=\"goog-text-highlight\">The Quebec PAH research group is made up of university professors, clinicians and fundamentalists, with varied but complementary and multidisciplinary expertise mainly covering epigenetics, metabolism, cellular response to stress and cardiopulmonary physiology and exercise. <\/span>This allows us to carry out transdisciplinary projects from the study of the gene and its regulation to the establishment of clinical trials.[\/vc_column_text][vc_empty_space height=&#8221;30px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div id='ins-image-box69fa15e5119cf' class='ins-image-box-wrapper ins-image-box-style-1 text-center   ' ><div class='ins-image-box-inner'><div class='ins-image-box-img text-center'><a class='ins-image-box-img-link' href='#rowSB' target='_self'><img src='https:\/\/phrg.ca\/wp-content\/uploads\/2020\/04\/Bonnet-S\u00e9bastien-scaled.jpg' alt='image-box'><\/a><\/div><div class='ins-image-content-wrapper last-paragraph-no-margin'><div class='ins-image-box-content-inner'><div class='ins-image-box-title margin-10px-bottom'><h6 class='ins-image-box-title-inner letter-spacing-05 title-font font-weight-500 display-block margin-0px-bottom  text-extra-large default'><span class='ins-image-box-number'><\/span> S\u00e9bastien Bonnet<\/h6><\/div><\/div><\/div><\/div><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div id='ins-image-box69fa15e511edd' class='ins-image-box-wrapper ins-image-box-style-1 text-center   ' ><div class='ins-image-box-inner'><div class='ins-image-box-img text-center'><a class='ins-image-box-img-link' href='#rowSP' target='_self'><img src='https:\/\/phrg.ca\/wp-content\/uploads\/2020\/04\/Provencher-Steeve-scaled.jpg' alt='image-box'><\/a><\/div><div class='ins-image-content-wrapper last-paragraph-no-margin'><div class='ins-image-box-content-inner'><div class='ins-image-box-title margin-10px-bottom'><h6 class='ins-image-box-title-inner letter-spacing-05 title-font font-weight-500 display-block margin-0px-bottom  text-extra-large default'><span class='ins-image-box-number'><\/span> Steeve Provencher<\/h6><\/div><\/div><\/div><\/div><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div id='ins-image-box69fa15e512120' class='ins-image-box-wrapper ins-image-box-style-1 text-center   ' ><div class='ins-image-box-inner'><div class='ins-image-box-img text-center'><a class='ins-image-box-img-link' href='#rowOB' target='_self'><img src='https:\/\/phrg.ca\/wp-content\/uploads\/2023\/10\/OlivierB-portrait2-1.jpeg' alt='image-box'><\/a><\/div><div class='ins-image-content-wrapper last-paragraph-no-margin'><div class='ins-image-box-content-inner'><div class='ins-image-box-title margin-10px-bottom'><h6 class='ins-image-box-title-inner letter-spacing-05 title-font font-weight-500 display-block margin-0px-bottom  text-extra-large default'><span class='ins-image-box-number'><\/span> Olivier Boucherat<\/h6><\/div><\/div><\/div><\/div><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div id='ins-image-box69fa15e5125ec' class='ins-image-box-wrapper ins-image-box-style-1 text-center   ' ><div class='ins-image-box-inner'><div class='ins-image-box-img text-center'><a class='ins-image-box-img-link' href='#rowFP' target='_self'><img src='https:\/\/phrg.ca\/wp-content\/uploads\/2023\/10\/FP-pic2.jpeg' alt='image-box'><\/a><\/div><div class='ins-image-content-wrapper last-paragraph-no-margin'><div class='ins-image-box-content-inner'><div class='ins-image-box-title margin-10px-bottom'><h6 class='ins-image-box-title-inner letter-spacing-05 title-font font-weight-500 display-block margin-0px-bottom  text-extra-large default'><span class='ins-image-box-number'><\/span> Fran\u00e7ois Potus<\/h6><\/div><\/div><\/div><\/div><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;]<div id='ins-image-box69fa15e512897' class='ins-image-box-wrapper ins-image-box-style-1 text-center   ' ><div class='ins-image-box-inner'><div class='ins-image-box-img text-center'><a class='ins-image-box-img-link' href='#rowAR' target='_self'><img src='https:\/\/phrg.ca\/wp-content\/uploads\/2025\/10\/Pic-20250908-Antenor_Rodrigues-scaled.jpg' alt='image-box'><\/a><\/div><div class='ins-image-content-wrapper last-paragraph-no-margin'><div class='ins-image-box-content-inner'><div class='ins-image-box-title margin-10px-bottom'><h6 class='ins-image-box-title-inner letter-spacing-05 title-font font-weight-500 display-block margin-0px-bottom  text-extra-large default'><span class='ins-image-box-number'><\/span> Antenor Rodrigues<\/h6><\/div><\/div><\/div><\/div><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[\/vc_column_inner][vc_column_inner width=&#8221;1\/6&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; color_scheme=&#8221;white&#8221; css=&#8221;.vc_custom_1604060255688{margin-top: 40px !important;background-image: url(https:\/\/phrg.ca\/wp-content\/uploads\/2020\/10\/iStock-1173329540-m1.png?id=16221) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column width=&#8221;1\/12&#8243;][\/vc_column][vc_column width=&#8221;10\/12&#8243;][vc_column_text css=&#8221;.vc_custom_1604152324049{margin-top: 20px !important;margin-bottom: 50px !important;}&#8221;]<\/p>\n<h4 style=\"text-align: center;\"><em><span class=\"goog-text-highlight\">The success of our group depends on the work of a team<br \/>\nof dedicated principal investigators, research coordinators and students.<br \/>\nEvery day, each of them contributes to our success.<\/span><\/em><\/h4>\n<p style=\"text-align: center;\">S\u00e9bastien Bonnet, PhD<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/12&#8243;][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1584991092309{margin-bottom: 20px !important;}&#8221; el_id=&#8221;rowSB&#8221;][vc_column][vc_empty_space height=&#8221;80px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;15419&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_shadow_border&#8221; onclick=&#8221;link_image&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;]<div id='ins-heading-69fa15e512cf3' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '>S\u00e9bastien Bonnet Ph. D., FAHA<\/h3><h6 class='section-heading-subtitle title-font  default '>Principal Investigator<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Full Professor, Faculty of medicine, Laval University<br \/>\nDirector of the Canadian research Chair in translational research in pulmonary vascular diseases<\/p>\n<p><b>Interests:<br \/>\n<\/b>Pulmonary arterial hypertension (PAH); chronic obstructive pulmonary disease (COPD); coronary disease.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_tour style=&#8221;modern&#8221; color=&#8221;peacoc&#8221; spacing=&#8221;5&#8243; gap=&#8221;10&#8243; active_section=&#8221;1&#8243; pagination_style=&#8221;flat-rounded&#8221; pagination_color=&#8221;sky&#8221; css_animation=&#8221;fadeIn&#8221;][vc_tta_section title=&#8221;Career path&#8221; tab_id=&#8221;sb-career-path&#8221;]<div id='ins-heading-69fa15e512d1a' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Career path<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<span lang=\"EN-CA\">After completing a PhD in vascular pathophysiology in France and a postdoctoral fellowship in vascular biology in Alberta, Dr. Bonnet settled in Quebec. He first held the position of Associate Professor at the Faculty of Medicine of Universit\u00e9 Laval and researcher at the IUCPQ Research Center, before becoming Full Professor and FRQS Researcher of Merit, where he continues his work on cardiovascular pathologies.<\/span><\/p>\n<p><span lang=\"EN-CA\">Professor Bonnet was appointed Fellow of the American Heart Association and Director of the Research Chair in Vascular Pathologies with Remodeling. This title, one of the most prestigious in the scientific community, is awarded to researchers who have demonstrated leadership, creativity, and excellence in the field of fundamental and clinical cardiovascular health research.<\/span><\/p>\n<p><span lang=\"EN-CA\">Dr. Bonnet is also interested in coronary artery diseases and heart failure. His promising discoveries in these fields have been published in internationally renowned scientific journals such as <i>Science Translational Medicine and Nature Cardiovascular Research.<\/i><\/span><\/p>\n<p><span lang=\"EN-CA\">Professor Bonnet&#8217;s research led to the discovery of the mechanism responsible for pulmonary arterial hypertension, a serious disease that primarily affects young adults. His team has also identified two promising substances for the treatment of this condition.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Work description&#8221; tab_id=&#8221;sb-work-description&#8221;]<div id='ins-heading-69fa15e512d4b' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Work description<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]The group of Dr. Bonnet uses a multidisciplinary and translational approach (from genes to population) in order to study the molecular and cellular mechanisms involved in the development of the process of vascular and bronchial remodeling. This work allows the identification of new biomarkers, thus improving the identification and clinical management of individuals afflicted by PAH. His research also identified new therapeutic targets such as Pim-1, miR-204 or PARP-1 in PAH. In addition, numerous works carried out in the laboratory of Dr. Bonnet aim at evaluating the impact of these targets in the COPD and the coronary diseases which have several similarities with PAH.<\/p>\n<p>The recent association of Drs Bonnet and Provencher creating the pulmonary hypertension research group offers new prospects of research in PAH. Indeed, the association of the fundamental research of Dr. Bonnet to the clinical research of Dr. Provencher allows research projects initiated in the laboratory to reach the patient&#8217;s bedside which will accelerate, without any doubt, the discovery of new therapies.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Awards and distinctions&#8221; tab_id=&#8221;sb-awards-and-distinctions&#8221;]<div id='ins-heading-69fa15e512d6e' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Awards and distinctions<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ol>\n<li>Virtuose de la sant\u00e9, Tribute to underline the remarkable contribution of honored researchers, their dedication in research and in training high caliber succession in health sciences, Laval University, 2022<\/li>\n<li>Yves Morin Price, awarded to highlight the quality of its supervision of graduate students for residents and the transmission of his passion for research, Faculty of Medicine, Laval University, 2019<\/li>\n<li>Recognition award, scientific chair of Pulmonary Vascular Research Institute annual congress, 2019<\/li>\n<li>Chair elect program committee of the American Thoracic Society (2018-2020)<\/li>\n<li>Chair SCILL committee of the American Heart Association (2017-2019)<\/li>\n<li>Pulmonary Vascular Research Institute North America representative, 2019<\/li>\n<li>Pulmonary Vascular Research Institute Research award, 2017<\/li>\n<li>European Respiratory Society Research Award on Pulmonary Hypertension, 2015<\/li>\n<li>Prix Louise Rousselle-Trottier awarded by Fondation des maladies du coeur et de l&#8217;AVC-Qu\u00e9bec for his study entitled &#8221; Role for DNA damage signalling in Pulmonary Hypertension&#8221;. This award of excellence is given to the researcher who has attained the highest rating evaluation for a research project on hypertension, 2014<\/li>\n<li>&#8220;Jonathan Ballon&#8221; Award from the Heart and Stroke Foundation &#8211; Qu\u00e9bec, for the highest rated scientific research project: &#8220;Role of miRNAs in pulmonary hypertension&#8221;, 2013<\/li>\n<li>Nominated for the Springer Junior Investigator Award of the North Amarican Vascular Biology Organization (NAVBO), 2012<\/li>\n<li>Honored and distinguished member of pulmonary hypertension association, 2011<\/li>\n<li>American Heart Association best abstract award, 2011<\/li>\n<li>Nominated as fellow of the American Heart Association, 2011<\/li>\n<li>SQHA young investigator award, 2011<\/li>\n<li>Best Canadian Researcher of the month of December by CHR, 2010<\/li>\n<li>Hypertension Canada young investigator award, 2010<\/li>\n<li>Canadian Cardiovascular Society young investigator award, 2010<\/li>\n<li>The Cardiovascular Health Network (CHN) &#8211; Pfizer Canada Grant for the Future award, 2019<\/li>\n<li>American Heart Association best abstract award, 2009<\/li>\n<li>Heart and Stroke Foundation of Canada New Investigator Salary Award, 2008<\/li>\n<li>Paul Mann Award for Translational Research, 2006<\/li>\n<li>Fraser Mustard Award from CIHR, 2005<\/li>\n<li>American Heart Association Cournand &amp; Comoroe Young Investigator Award, 2004<\/li>\n<\/ol>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_tta_section][vc_tta_section title=&#8221;Grants&#8221; tab_id=&#8221;sb-grants&#8221;]<div id='ins-heading-69fa15e512d8f' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Grants<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ul>\n<li>IRSC: Targeting Hypusine signaling: an opportunity to counter vascular remodelling in pulmonary arterial hypertension (2023-2028)<\/li>\n<li>IRSC: Exploring the interplay between metabolic and Epigenetic signaling pathways to regulate neointima hyperplasia (2023-2028)<\/li>\n<li>CIHR: The anti-oxidative DNA damage protein MTH1, the novel pulmonary hypertension Achilles heel (2020-2025)<\/li>\n<li>FRQS: \u00c9tude de la physiopathologie de l&#8217;hypertension art\u00e9rielle pulmonaire et d&#8217;insuffisance cardiaque droite (2021-2025<\/li>\n<li>IRSC: Replication stress and pulmonary hypertension: Role for checkpoint kinase 1 (2018-2023)<\/li>\n<li>FMCC: Role for FOXM1 in DNA damage response and cell survival in pulmonary hypertension (2014-2017)(2017-2020)<\/li>\n<li>CRC: Recherche translationnelle en maladies vasculaires pulmonaires (2015-2020)<\/li>\n<li>IRSC : Role for miRNA in pulmonary hypertension (2012-2017)<\/li>\n<li>CRC : Vascular remodeling diseases (2010-2015)<\/li>\n<li>FMCC : miR-204 in pulmonary hypertension (2011-2014)<\/li>\n<li>IRSC : Experimental therapies for vasculare remodeling diseases (2008-2013)<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1584991100411{margin-bottom: 20px !important;}&#8221; el_id=&#8221;rowSP&#8221;][vc_column][vc_empty_space height=&#8221;80px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;15439&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_shadow_border&#8221; onclick=&#8221;link_image&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;]<div id='ins-heading-69fa15e512daf' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '>Steeve Provencher, M.D., M. Sc., FRCPC<\/h3><h6 class='section-heading-subtitle title-font  default '>Principal Investigator<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Pulmonologist<br \/>\nDirector of the\u00a0Pulmonology\u00a0Research Axis at the IUCPQ-UL Research Center<br \/>\nDirector, Pulmonary Hypertension Program<br \/>\nAssociate Professor, Faculty of Medicine, Universit\u00e9 Laval<br \/>\nPrincipal Investigator<\/p>\n<p><b>Interests :<\/b><br \/>\nPulmonary arterial hypertension, exercise physiology, muscle adaptation, hemodynamics, pulmonary embolism[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_tour style=&#8221;modern&#8221; color=&#8221;peacoc&#8221; spacing=&#8221;5&#8243; gap=&#8221;10&#8243; active_section=&#8221;1&#8243; pagination_style=&#8221;flat-rounded&#8221; pagination_color=&#8221;sky&#8221; css_animation=&#8221;fadeIn&#8221;][vc_tta_section title=&#8221;Career path&#8221; tab_id=&#8221;sp-career-path&#8221;]<div id='ins-heading-69fa15e512dce' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Career path<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]After completing his specialty in pulmonology and a master\u2019s degree in experimental medicine, Dr.Provencher completed two years of post-doctoral training in pulmonary hypertension at the Antoine B\u00e9cl\u00e8re Hospital in France. Since his return, he has been director of the pulmonary hypertension program at Laval University in Quebec City. His research program focuses on the pathophysiology of exercise, as well as the mechanisms leading to the development of pulmonary arterial hypertension.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Work description&#8221; tab_id=&#8221;sp-work-description&#8221;]<div id='ins-heading-69fa15e512ded' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Work description<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Dr. Provencher is working on the mechanisms of stress intolerance in pulmonary arterial hypertension. In collaboration with his colleague, Professor S\u00e9bastien Bonnet, he is also interested in the mechanisms leading to the development of pulmonary arterial hypertension, as well as the clinical validation of biomarkers of this disease. Together, in clinical trials, they are currently evaluating the clinical effects of two new treatments from their pulmonary hypertension laboratory. His interests in exercise pathophysiology and biomarkers have also led to work on pulmonary embolism, post-pneumonectomy and chronic obstructive pulmonary disease.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Awards and distinctions&#8221; tab_id=&#8221;sp-awards-and-distinctions&#8221;]<div id='ins-heading-69fa15e512e0c' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Awards and distinctions<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ol>\n<li>Yves Morin Award, awarded to recognize the quality of the supervision of graduate students or residents as well as the transmission of his passion for research. Faculty of Medicine, Universit\u00e9 Laval 2019<\/li>\n<li>Award of Recognition, leading the scientific program of the Pulmonary Vascular Research Institute Annual Conference, January 2019<\/li>\n<li>Recipient of a Senior FRSQ Fellowship as a clinician-researcher from 2015 to 2019 entitled \u201cPulmonary Arterial Hypertension: A Translational and Multidisciplinary Approach\u201d.<\/li>\n<li>Jacques Leblanc Award (nominee), awarded to the Director of Research with the highest level of excellence in student education (2011).<\/li>\n<li>Marc Julien Recognition Award, awarded by the Internal Medicine Residents of Laval University (2011) in recognition of the outstanding work done in teaching hospitals with residents, dedication to its patients, clinical competence, and quality of care.<\/li>\n<li>Fran\u00e7ois Brenot Award from the European Respiratory Society (2004), recognizing the most promising young investigator in the field of vascular pulmonary sciences.<\/li>\n<\/ol>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_tta_section][vc_tta_section title=&#8221;Contributions and activities&#8221; tab_id=&#8221;sp-contributions-and-activities&#8221;]<div id='ins-heading-69fa15e512e30' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Contributions and activities<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Director of the Pulmonology Research Axis at the IUCPQ-UL Research Center<\/p>\n<p>Member of the World Symposium\u2019s Canadian Practice Guidelines Committee on Pulmonary Vascular Disease and International Practice Guides.<\/p>\n<p>Research Committee Chair, PHA Canada<\/p>\n<p>Associate Editor of European Respiratory Review and Respiratory Medicine &amp; Research.<\/p>\n<p>Member of the editorial board of the European Respiratory Journal and editor for many scientific journals.<\/p>\n<p>Jury member of granting agencies, including Fonds de Recherche en Sant\u00e9 du Qu\u00e9bec, PSI Foundation, Medical Research Scotland and Netherlands Asthma Foundation.<\/p>\n<p>Over 150 conferences invited to provincial, national and international conferences.<\/p>\n<p>Organizer of several provincial, national and international medical conferences.<\/p>\n<p>Head of Pulmonology Division, Department of Medicine, Universit\u00e9 Laval[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Grants&#8221; tab_id=&#8221;sp-grants&#8221;]<div id='ins-heading-69fa15e512e4e' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Grants<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ul>\n<li>IUCPQ-UL Foundation: ACLY inhibition in pulmonary arterial hypertension: a pilot study (2024)<\/li>\n<li>CIHR: Targeting Mitosis in PAH: A New Approach to Therapy (2023-2028)<\/li>\n<li>FRQS: Hypusine signaling in IPF-PH (2022-2023)<\/li>\n<li>CMREF: PARP-1\/PKM2 axis: a multitasking stress modulator and exciting new therapeutic target in pulmonary hypertension-induced right ventricular failure (2022-2023)<\/li>\n<li>IUCPQ-UL Foundation: Role of CHK1\/2 in pulmonary vascular remodeling contributing to pulmonary hypertension related to pulmonary fibrosis (2020-2021)<\/li>\n<li>IRSC: BET inhibition in PAH: a phase 2 clinical trial (2019-2024)<\/li>\n<li>IRSC: PARP inhibition in PAH: A Phase 1 clinical trial (2018-2021)<\/li>\n<li>IRSC: RUNX2-related pulmonary artery remodeling and calcification in pulmonary arterial hypertension (2015-2020)<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1584991122301{margin-bottom: 20px !important;}&#8221; el_id=&#8221;rowOB&#8221;][vc_column][vc_empty_space height=&#8221;80px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;17242&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_shadow_border&#8221; onclick=&#8221;link_image&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;]<div id='ins-heading-69fa15e512e70' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '>Olivier Boucherat, Ph. D.<\/h3><h6 class='section-heading-subtitle title-font  default '>Principal investigator<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Adjunct assistant Professor, Faculty of Medicine, Laval University<\/p>\n<p><strong>Interests:<\/strong><br \/>\nPulmonary hypertension, lung development and alterations[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_tour style=&#8221;modern&#8221; color=&#8221;peacoc&#8221; spacing=&#8221;5&#8243; gap=&#8221;10&#8243; active_section=&#8221;1&#8243; pagination_style=&#8221;flat-rounded&#8221; pagination_color=&#8221;sky&#8221; css_animation=&#8221;fadeIn&#8221;][vc_tta_section title=&#8221;Career path&#8221; tab_id=&#8221;ob-career-path&#8221;]<div id='ins-heading-69fa15e512e8d' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Career path<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]During his PhD training at the University of Paris Est in France, Dr. Boucherat worked on bronchopulmonary dysplasia (BPD) and congenital diaphragmatic hernia (CDH), both of which representing are major concerns in the respiratory care of neonates complicated by pulmonary arterial hypertension (PAH).<\/p>\n<p>He then moved to Canada for a postdoctoral fellowship in Dr. Jeannotte\u2019s laboratory in the department of Molecular Biology, Medical Biochemistry, and Pathology in Hotel Dieu Research center, Quebec City. Using genetically modified mice, \u201cOmic\u201d technologies, embryonic lung organ culture, and molecular strategies to achieve gain and loss of function both <em>in vivo<\/em> and <em>in vitro<\/em>, he initiated and carried through to publication a series of research studies demonstrating the implication of multiple oncogenic signals in the development of lung diseases. After completing his postdoctoral fellowship, Dr. Boucherat joined the pulmonary hypertension research group led by Drs Bonnet and Provencher to better understand the pathogenesis of PAH, identify targets, and validate therapeutic tools.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Work description&#8221; tab_id=&#8221;ob-work-description&#8221;]<div id='ins-heading-69fa15e512eaa' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Work description<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Dr. Boucherat\u2019s research program is designed to <strong>1)<\/strong> elucidate the molecular mechanisms that drive pulmonary vascular and cardiac remodeling in group 1 and 3 PH: a prerequisite to identify new promising targets; and <strong>2)<\/strong> find new circulating markers that could be used to aid in diagnosis, prognosis and treatment of patients.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Awards and distinctions&#8221; tab_id=&#8221;ob-awards-and-distinctions&#8221;]<div id='ins-heading-69fa15e512ec6' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Awards and distinctions<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ol>\n<li>Abstract Poster Young investigator Award, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, January 2019<\/li>\n<li>New investigator Salary Grant from the Heart and Stroke Foundation, 2018 (declined)<\/li>\n<li>Aldrighetti Research Award for young investigator, Pulmonary Hypertension Association, April 2017<\/li>\n<li>Finalist of the Cournand and Comroe award from the American Heart Association (AHA), 2016<\/li>\n<li>ENTELLIGENCE young investigator award, 2016<\/li>\n<\/ol>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_tta_section][vc_tta_section title=&#8221;Grants&#8221; tab_id=&#8221;ob-grants&#8221;]<div id='ins-heading-69fa15e512ee2' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Grants<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ul>\n<li>CIHR: Targeting Integrin Signaling to Alleviate Remodeling in Pulmonary Arteries and the right Ventricle in Pulmonary Hypertension (2024-2030)<\/li>\n<li>IRSC: Targeting mitosis and senescence to reverse pulmonary hypertension ; a promising therapeutic strategy (2024-2031)<\/li>\n<li>FRQS: Identification de nouvelles cibles th\u00e9rapeutiques pour corriger le remodelage pulmonaire et cardiaque associ\u00e9 \u00e0 l&#8217;hypertension pulmonaire (2022-2026)<\/li>\n<li>IRSC: ATP Citrate Lyase ; an attractive target at the nexus of metabolic and epigenetic alterations in pulmonary arterial hypertension (2022-2027)<\/li>\n<li>MITACS: R\u00f4le de l&#8217;axe Acly-P300 en hypertension pulmonaire (2021-2024)<\/li>\n<li>IRSC: The anti-oxidative DNA damage protein MTH1, the novel pulmonary hypertension achilles heel (2020-2025)<\/li>\n<li>APQ-FQSR: Targeting PRC2 for treating PAH (2019-2020)<\/li>\n<li>IRSC: Role of the long non-coding RNA H19 as a novel biomarker and therapeutic target in RV failure in PAH (2019-2024)<\/li>\n<li>FRQS: Targeting mechanisms that drive PAH cells&#8217; survival proliferation (2018-2022) (bourse salariale + subvention de recherche)<\/li>\n<li>CMREF: Targeting replication stress coping mechanisms in PAH (2017-2019)<\/li>\n<li>ATS: Forkhead-box (FOX) transcription factors in pulmonary arterial hypertension (2017-2019)<\/li>\n<li>ENTELLIGENCE: Impact of Heat Shock Protein 90 inhibition in pulmonary arterial hypertension (2016-2017)<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1585138948619{margin-bottom: 20px !important;}&#8221; el_id=&#8221;rowFP&#8221;][vc_column][vc_empty_space height=&#8221;80px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;17214&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_shadow_border&#8221; onclick=&#8221;link_image&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;]<div id='ins-heading-69fa15e512f02' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '>Fran\u00e7ois Potus, Ph. D.<\/h3><h6 class='section-heading-subtitle title-font  default '>Principal investigator<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Adjunct assistant Professor, Faculty of Medicine, Laval University<\/p>\n<p><strong>Interests:<\/strong><br \/>\nPulmonary arterial hypertension, right heart failure, Methylation and genetic expression[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_tour style=&#8221;modern&#8221; color=&#8221;peacoc&#8221; spacing=&#8221;5&#8243; gap=&#8221;10&#8243; active_section=&#8221;1&#8243; pagination_style=&#8221;flat-rounded&#8221; pagination_color=&#8221;sky&#8221; css_animation=&#8221;fadeIn&#8221;][vc_tta_section title=&#8221;Career path&#8221; tab_id=&#8221;fp-career-path&#8221;]<div id='ins-heading-69fa15e512f20' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Career path<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Between 2005 and 2011, he pursued studies in medical sciences and biology at several French universities, including Jean Monnet University (Saint-\u00c9tienne), Blaise Pascal University (Clermont-Ferrand), and Claude Bernard University (Lyon 1). He specialized in physiology, genetics, and cell biology, earning both Bachelor&#8217;s and Master&#8217;s degrees. His early research experience includes a fellowship at the Roanne Hospital Center and the IGFL\/CNRS in Lyon, where he contributed to projects on nuclear receptor ERR\u03b1 and its regulatory mechanisms. His work led to the development of a biochemistry exploration protocol presented at the JIB conference in Paris.<\/p>\n<p>His academic journey continued with a Ph.D. at Laval University, where he explored the role of microRNAs and bromodomain proteins in pulmonary arterial hypertension (PAH). He then completed postdoctoral training at Queen\u2019s University, investigating DNA methylation and its impact on PAH and right heart failure.<\/p>\n<p>Since joining the IUCPQ PH Research Group in 2020, he has launched an independent research program, secured major funding including CIHR grants, and created Canada\u2019s first PAH multi-omic database in collaboration with national biobanks and industry partners.<\/p>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Work description&#8221; tab_id=&#8221;fp-work-description&#8221;]<div id='ins-heading-69fa15e512f3b' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Work description<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Awards and distinctions&#8221; tab_id=&#8221;fp-awards-and-distinctions&#8221;]<div id='ins-heading-69fa15e512f56' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Awards and distinctions<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ol>\n<li>3CPR best Abstract decerned to his PhD student Victoria Toro, AHA, Boston, USA, November 2021<\/li>\n<li>Presentation Award decerned to his PhD student Victoria Toro, Quebec respiratory health research network meeting, Qu\u00e9bec City, Canada, November 2021<\/li>\n<li>Best oral presentation decerned to his PhD student Victoria Toro, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, June 2021<\/li>\n<li>Pulmonary Circulation Travel Award, ATS, Philadelphia, USA, May 2020<\/li>\n<li>Jane Morse Award for the best Abstract, ATS, Dallas, USA. May 2019<\/li>\n<li>Pulmonary Circulation Travel Award, ATS, Dallas, USA, May 2019<\/li>\n<li>Courmand and Comroe Young Investigator Award, AHA, Chicago, USA, November 2018<\/li>\n<li>Abstract Scholarship, Pulmonary Circulation, ATS, San Diego, USA, May 2018<\/li>\n<li>Faculty of graduate studies honor roll, Faculty of Medicine, Universit\u00e9 Laval, Qu\u00e9bec City, 2017<\/li>\n<li>3CPR junior investigator travel stipend, AHA, New Orleans, USA, November 2016<\/li>\n<li>PhD oral presentation Award, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, June 2016<\/li>\n<li>Travel Award respiratory health network from FRQS for ATS, San Francisco, USA, May 2016<\/li>\n<li>Abstract scholarship, Pulmonary Circulation, ATS, Denver, USA, May 2015<\/li>\n<li>Award for publication as first author, medical department, Universit\u00e9 Laval, Qu\u00e9bec City, Canada, March 2015<\/li>\n<li>Cardiopulmonary best Abstract Award, AHA, Chicago, USA, November 2014<\/li>\n<li>Excellence Award, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, June 2014<\/li>\n<li>James C. Hogg Award of the Canadian Thoracic Society, ATS, San Diego, USA, May 2014<\/li>\n<li>Travel Award respiratory health network from FRQS for ATS, San Diego, USA, May 2014<\/li>\n<li>Grant Pierce Biomedical, cardiovascular forum, Louisville, USA, August 2013 (declined)<\/li>\n<li>First price, PhD oral presentation, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, May 2013<\/li>\n<li>Young investigator Award, Grover, ATS, Sedalia, USA, September 2013<\/li>\n<li>Recongnition Award, American Physiology Society, Cardiovascular Research section, Experimental Biology (EB), Boston, USA, April 2013<\/li>\n<li>Merck Award, Scientific University research day CRIUCPQ, Qu\u00e9bec City, Canada, June 2012<\/li>\n<\/ol>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_tta_section][vc_tta_section title=&#8221;Grants&#8221; tab_id=&#8221;pf-grants&#8221;]<div id='ins-heading-69fa15e512f70' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Grants<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ul>\n<li>FRQS : From methylation to gene expression, a multi-omics approach for the development of new tools &#8211; Junior 2, Universit\u00e9 Laval (2023-2027)<\/li>\n<li>FRQS : From methylation to gene expression, a multi-omics approach for the development of new diagnostic and therapeutic tools in pulmonary hypertension &#8211; Junior 1, Universit\u00e9 Laval (2023-2027)<\/li>\n<li>IRSC : Epigenome wide study for the investigation of DNA methylation as therapeutic target and novel biomarker of pulmonary arterial hypertension, Universit\u00e9 Laval (2022-2027)<\/li>\n<li>IRSC : Dysregulation of TET2 and DNMT3A promotes pulmonary arterial hypertension through inflammation, Queen&#8217;s University (2020-2026)<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1759773429310{margin-bottom: 20px !important;}&#8221; el_id=&#8221;rowAR&#8221;][vc_column][vc_empty_space height=&#8221;80px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;17524&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_shadow_border&#8221; onclick=&#8221;link_image&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;]<div id='ins-heading-69fa15e512f8a' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '>Antenor Luiz Lima Rodrigues, Ph. D.<\/h3><h6 class='section-heading-subtitle title-font  default '>Principal investigator<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Assistant Professor, Faculty of Medicine, Laval University<\/p>\n<p><strong>Interests:<\/strong><\/p>\n<p>Respiratory Physiology, Pulmonary Rehabilitation, Physical Therapy, Pulmonary Arterial hypertension, COPD[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_tour style=&#8221;modern&#8221; color=&#8221;peacoc&#8221; spacing=&#8221;5&#8243; gap=&#8221;10&#8243; active_section=&#8221;1&#8243; pagination_style=&#8221;flat-rounded&#8221; pagination_color=&#8221;sky&#8221; css_animation=&#8221;fadeIn&#8221;][vc_tta_section title=&#8221;Career path&#8221; tab_id=&#8221;1759773416952-f2ff19d3-fce1&#8243;]<div id='ins-heading-69fa15e512fa4' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Career path<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]Antenor Rodrigues holds a Ph.D. in Rehabilitation Sciences from the State University of Londrina (Brazil), where he specialized in pulmonary rehabilitation for individuals with chronic respiratory diseases such as COPD. He also completed a Master&#8217;s degree and a specialization in respiratory physiotherapy in the same institution.<\/p>\n<p>Following his doctorate, he pursued two postdoctoral fellowships. The first fellowship, at the University of Toronto, focused on respiratory physiotherapy and rehabilitation approaches. The second fellowship, conducted at St. Michael&#8217;s Hospital in Toronto and funded by the CIHR, was centered on advances in respiratory physiology in critical care. He subsequently held a position as a research associate within the same team, where he further developed his work on patient-ventilator interaction and respiratory muscle assessment.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Work description&#8221; tab_id=&#8221;1759773417010-f870df1e-4e16&#8243;]<div id='ins-heading-69fa15e512fc0' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Work description<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]His current research focuses on the pathophysiology of respiratory and locomotor muscle dysfunction across the spectrum of disease severity, from rehabilitation to intensive care. He is particularly interested in the mechanisms underlying exercise intolerance and respiratory muscle overload in chronic and acute respiratory conditions, including pulmonary hypertension, COPD and critical illness. His approach integrates advances physiological assessments, including electromyography (EMG), near-infrared spectroscopy (NIRS), and dynamic respiratory measurements, to investigate muscle function, oxygen delivery and ventilatory mechanics. He also explores how targeted rehabilitation interventions and ventilatory support strategies can improve patient outcomes, reduce dyspnea and optimize recovery.<\/p>\n<p>By bridging fundamental physiology with clinical practice, Dr Rodrigues aims to develop personalized therapeutic strategies to improve functional capacity, reduce dyspnea, and optimize quality of life in patients with respiratory limitations.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Awards and distinctions&#8221; tab_id=&#8221;1759773417052-3c6f554a-c415&#8243;]<div id='ins-heading-69fa15e512fdb' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Awards and distinctions<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ol>\n<li>The John Laffey award for outstanding academic achievement and contribution to Critical Care Research, University of Toronto, 2024<\/li>\n<li>CIHR fellowship award, 2024<\/li>\n<li>Trainee research award from the interdepartmental division of critical care medicine, University of Toronto, 2023<\/li>\n<li>Emerging investigator award for investigators who have contributed to content published in AJRCCM, 2023<\/li>\n<li>Early career professional highlight award, The ATS pulmonary Rehabilitation assembly early career professionals (ECPs), 2022<\/li>\n<li>Art Slustky research day finalist oral abstract presenter award, University of Toronto, 2022<\/li>\n<li>&#8220;Patrono&#8221; honor given to professor who is chosen by the students due to their broad knowledge, scientific and academic prominence, course of physical therapy, Pit\u00e1goras college, Londrina, Brazil, 2019<\/li>\n<li>European Respiratory Society Young scientific sponsorship award, ERS, 2017<\/li>\n<\/ol>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_tta_section][vc_tta_section title=&#8221;Grants&#8221; tab_id=&#8221;1759773417179-b4716cec-56ac&#8221;]<div id='ins-heading-69fa15e512ff3' class='section-heading ins-heading default default    '  style='margin-top:0; margin-bottom:0'><h3 class='section-heading-title margin-10px-top  default '><\/h3><h6 class='section-heading-subtitle title-font  default '>Grants<\/h6><\/div><script type=\"text\/javascript\">\n\t\t(function(jQuery) {\n\t\t\t\t\t})(jQuery);\n\t\t\t\t\t\t<\/script>[vc_column_text]<\/p>\n<ul>\n<li>SMHA AFP Innovation funds: Comparing standard and asymmetrical high flow nasal cannula versus non-invasive ventilation in the treatment of exacerbations of chronic obstructive pulmonary disease and hypercapnic respiratory failure, co-applicant (2025-2027)<\/li>\n<li>ATS: Asymmetrical high flow oxygen vs non-invasive ventilation in acute hypercapnic respiratory failure, co-applicant (2025-2026)<\/li>\n<li>The Cardiovascular Medical Research and Education Fund: Beyond remodeling: exploring sotatercept\u2019s multifaceted impact on pulmonary arterial hypertension outcomes, co-applicant (2025-2027)<\/li>\n<li>Getinge Research Grant: Susceptibility for entrainment; role of ventilator settings on the occurrence of reverse triggering and its physiological consequences, co-applicant (2025)<\/li>\n<li>Trainee Research award from the Interdepartmental Division of Critical Care of Medicine, fellowship, principal applicant (2023-2024)<\/li>\n<li>St. Michael&#8217;s Hospital Medical Services Association (SMHA) innovation funds: Physiological evaluation of accessory muscle activity and function after traumatic spinal cord injury: the ACCESSIT study, co-applicant (2023-2025)<\/li>\n<li>Team Breath Research award from the Lung Health Foundation: co-applicant (2022-2023)<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row css=&#8221;.vc_custom_1584807143299{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text]The Quebec PAH research group is made up of university professors, clinicians and fundamentalists, with varied but complementary and multidisciplinary expertise mainly covering epigenetics, metabolism, cellular response [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":16307,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-16313","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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